Victoza$526
Byetta$816
Wegovy$871
Trulicity$975
Ozempic$992
Rybelsus$995
Zepbound$1,052
Mounjaro$1,077
Saxenda$1,308
Victoza$526
Byetta$816
Wegovy$871
Trulicity$975
Ozempic$992
Rybelsus$995
Zepbound$1,052
Mounjaro$1,077
Saxenda$1,308

Ozempic vs Wegovy

Compare Ozempic and Wegovy on active ingredient, dosing schedule, FDA-approved use and pharmacy acquisition cost.

By Sam Reed · Founder and data leadVerified Aug 12, 2026

Ozempic

Novo Nordisk

Active ingredient
Semaglutide
Form
INJECTION, SOLUTION, TABLET
FDA-approved for
Type 2 diabetes, Cardiovascular risk reduction
$992
lowest package, pharmacy acquisition cost

Wegovy

Novo Nordisk

Active ingredient
Semaglutide
Form
INJECTION, SOLUTION, TABLET
FDA-approved for
Weight management, Cardiovascular risk reduction
$871
lowest package, pharmacy acquisition cost

The short answer

Ozempic and Wegovy both contain Semaglutide. They differ in approved use and dose, not in active ingredient — which is why the choice usually comes down to what your prescriber can justify and what your plan covers.

Side by side

Costs are what a pharmacy pays to acquire each product, from CMS NADAC. Not a retail price, and not what you would pay.

Ozempic
Wegovy
Lowest package cost
$992
$871
Active ingredient
Semaglutide
Semaglutide
Manufacturer
Novo Nordisk
Novo Nordisk
Form
INJECTION, SOLUTION, TABLET
INJECTION, SOLUTION, TABLET
FDA-approved for
Type 2 diabetes, Cardiovascular risk reduction
Weight management, Cardiovascular risk reduction
= better value on that rowScroll sideways on small screens — the first column stays pinned
Keep comparing
Data sources · cited with retrieval dates
  • CMS NADACNational Average Drug Acquisition Cost, weekly fileretrieved Aug 12, 2026
  • CMS Medicare Part DPrescriber public use file, by geography and drugretrieved Aug 12, 2026
  • CMS State Drug UtilizationQuarterly Medicaid prescription and reimbursement dataretrieved Aug 12, 2026

NADAC figures are pharmacy acquisition costs, not retail prices and not what you will pay. This content is educational and is not medical advice.