Victoza$526
Byetta$816
Wegovy$871
Trulicity$975
Ozempic$992
Rybelsus$995
Zepbound$1,052
Mounjaro$1,077
Saxenda$1,308
Victoza$526
Byetta$816
Wegovy$871
Trulicity$975
Ozempic$992
Rybelsus$995
Zepbound$1,052
Mounjaro$1,077
Saxenda$1,308

Byetta vs Compounded semaglutide

Compare Byetta and Compounded semaglutide on active ingredient, dosing schedule, FDA-approved use and pharmacy acquisition cost.

By Sam Reed · Founder and data leadVerified Feb 11, 2026

Byetta

AstraZeneca

Active ingredient
Exenatide
Form
INJECTION
FDA-approved for
Type 2 diabetes
$816
lowest package, pharmacy acquisition cost

Compounded semaglutide

Compounded — no single manufacturer

Active ingredient
Semaglutide
Form
FDA-approved for
Not an FDA-approved product
Not NADAC-indexed
lowest package, pharmacy acquisition cost

The short answer

Byetta contains Exenatide and Compounded semaglutide contains Semaglutide. These are different molecules, so their dosing and clinical evidence differ.

Side by side

Costs are what a pharmacy pays to acquire each product, from CMS NADAC. Not a retail price, and not what you would pay.

Byetta
Compounded semaglutide
Lowest package cost
$816
Not NADAC-indexed
Active ingredient
Exenatide
Semaglutide
Manufacturer
AstraZeneca
Compounded
Form
INJECTION
FDA-approved for
Type 2 diabetes
Not FDA-approved
= better value on that rowScroll sideways on small screens — the first column stays pinned
Keep comparing
Data sources · cited with retrieval dates
  • CMS NADACNational Average Drug Acquisition Cost, weekly fileretrieved Feb 11, 2026
  • CMS Medicare Part DPrescriber public use file, by geography and drugretrieved Feb 11, 2026
  • CMS State Drug UtilizationQuarterly Medicaid prescription and reimbursement dataretrieved Feb 11, 2026

NADAC figures are pharmacy acquisition costs, not retail prices and not what you will pay. This content is educational and is not medical advice.