Compounded semaglutide vs Mounjaro

Compare Compounded semaglutide and Mounjaro on active ingredient, dosing schedule, FDA-approved use and pharmacy acquisition cost.

By Sam Reed · Founder and data leadVerified Aug 12, 2026

Compounded semaglutide

Compounded — no single manufacturer

Active ingredient: Semaglutide
Form: —
FDA-approved for: Not an FDA-approved product

Not NADAC-indexed

lowest package, pharmacy acquisition cost

Mounjaro

Eli Lilly

Active ingredient: Tirzepatide
Form: INJECTION, SOLUTION
FDA-approved for: Type 2 diabetes

$1,077

lowest package, pharmacy acquisition cost

The short answer

Compounded semaglutide contains Semaglutide and Mounjaro contains Tirzepatide. These are different molecules, so their dosing and clinical evidence differ.

Side by side

Costs are what a pharmacy pays to acquire each product, from CMS NADAC. Not a retail price, and not what you would pay.

Compounded semaglutide

Mounjaro

Lowest package cost

Not NADAC-indexed

$1,077

Active ingredient

Semaglutide

Tirzepatide

Manufacturer

Compounded

Eli Lilly

Form

—

INJECTION, SOLUTION

FDA-approved for

Not FDA-approved

Type 2 diabetes

= better value on that rowScroll sideways on small screens — the first column stays pinned

Keep comparing

Byetta vs Compounded semaglutide Byetta vs Mounjaro Compounded liraglutide vs Mounjaro

Data sources · cited with retrieval dates

CMS NADACNational Average Drug Acquisition Cost, weekly fileretrieved Aug 12, 2026
CMS Medicare Part DPrescriber public use file, by geography and drugretrieved Aug 12, 2026
CMS State Drug UtilizationQuarterly Medicaid prescription and reimbursement dataretrieved Aug 12, 2026

NADAC figures are pharmacy acquisition costs, not retail prices and not what you will pay. This content is educational and is not medical advice.